Please use this identifier to cite or link to this item:
Title: L-asparaginase induced intracranial haemorrhage in acute lymphoblastic leukemia
Authors: Lim, H.L.
Teo, C.P.
Wong, K.
Kueh, Y.K. 
Keywords: Acute lymphoblastic leukaemia
Intracranial haemorrhage
Issue Date: Feb-1998
Citation: Lim, H.L., Teo, C.P., Wong, K., Kueh, Y.K. (1998-02). L-asparaginase induced intracranial haemorrhage in acute lymphoblastic leukemia. Singapore Medical Journal 39 (2) : 76-78. ScholarBank@NUS Repository.
Abstract: A 20-year-old national serviceman with acute lymphoblastic leukaemia, developed a large left parieto-occipital haemorrhage 7 days after completion of induction chemotherapy. Severe hypofibrinogenemia had been noted while he was receiving L-asparaginase. The haemorrhage could not be attributed to thrombocytopenia, disseminated intravascular coagulopathy, arterio-venous malformation, berry aneurysm or leukaemic infiltration because each of these causes was carefully investigated into and excluded. We conclude that the intracranial haemorrhage was likely L-asparaginase induced, an uncommon but recognised complication associated with L-asparaginase therapy.
Source Title: Singapore Medical Journal
ISSN: 00375675
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

Page view(s)

checked on Nov 8, 2019

Google ScholarTM


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.