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Title: Visual function in Vogt-Koyanagi-Harada patients
Authors: Chee, S.-P. 
Luu, C.D.
Cheng Ching-Li, C.-L.
Lim, W.-K.
Jap, A.
Keywords: Vogt-Koyanagi-Harada
Issue Date: Aug-2005
Citation: Chee, S.-P., Luu, C.D., Cheng Ching-Li, C.-L., Lim, W.-K., Jap, A. (2005-08). Visual function in Vogt-Koyanagi-Harada patients. Graefe's Archive for Clinical and Experimental Ophthalmology 243 (8) : 785-790. ScholarBank@NUS Repository.
Abstract: Background: Vogt-Koyanagi-Harada (VKH) disease presents with anterior segment inflammation, choroiditis and exudative retinal detachment. Following resolution of the inflammation, VKH patients have been noted to complain of visual disturbances despite good visual acuity. We therefore investigated the visual function deficits of convalescent VKH patients. Methods: A cross-sectional observational nonrandomized controlled study of convalescent VKH patients from the Uveitis Service of the Singapore National Eye Centre, and normal subjects was performed. The best-corrected visual acuities (BCVA) and multifocal electroretinograms (mfERGs) of VKH patients with and without peripapillary atrophy (PPA) were compared with those of the normal eyes. The mfERG results were subdivided into those obtained from the peripapillary area and those from the rest of the macular. Results: Eleven VKH eyes with large PPA to disc ratios (PPA/D ratio >2), 15 VKH eyes with PPA/D ratios < 1 and 6 normal eyes were included in the study. Five eyes (54.5%) of VKH patients with PPA/D>2 had a BCVA of less than 20/40. All the other eyes had 20/20 vision. Nine of the 11 VKH eyes with PPA/D>2 also had large areas of chorioretinal atrophy. The mfERG responses of VKH eyes with PPA/D ratio >2 were markedly reduced in amplitude (p
Source Title: Graefe's Archive for Clinical and Experimental Ophthalmology
ISSN: 0721832X
DOI: 10.1007/s00417-005-1156-3
Appears in Collections:Staff Publications

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