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https://doi.org/10.1586/egh.09.48
| Title: | Therapeutic vaccination and novel strategies to treat chronic HBV infection | Authors: | Bertoletti, A. Gehring, A. |
Keywords: | PD-1 T-cell deletion T-cell exhaustion T-cell receptor therapy Treg Viral hepatitis |
Issue Date: | Oct-2009 | Citation: | Bertoletti, A., Gehring, A. (2009-10). Therapeutic vaccination and novel strategies to treat chronic HBV infection. Expert Review of Gastroenterology and Hepatology 3 (5) : 561-569. ScholarBank@NUS Repository. https://doi.org/10.1586/egh.09.48 | Abstract: | Therapeutic vaccination for the treatment of chronic hepatitis B has so far shown limited clinical efficacy. In this review, we argue that the principal cause of this failure is the profound defect of virus-specific T cells present in chronic hepatitis B patients and we discuss potential new ways to achieve an efficient restoration of virus-specific immunity in patients with chronic hepatitis B virus infection. © 2009 Expert Reviews Ltd. | Source Title: | Expert Review of Gastroenterology and Hepatology | URI: | http://scholarbank.nus.edu.sg/handle/10635/130161 | ISSN: | 17474124 | DOI: | 10.1586/egh.09.48 |
| Appears in Collections: | Staff Publications |
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