Please use this identifier to cite or link to this item:
https://scholarbank.nus.edu.sg/handle/10635/129603
DC Field | Value | |
---|---|---|
dc.title | Age-related reference intervals for free and total prostate-specific antigen in a Singaporean population | |
dc.contributor.author | Saw, S. | |
dc.contributor.author | Aw, T.-C. | |
dc.date.accessioned | 2016-11-08T08:24:28Z | |
dc.date.available | 2016-11-08T08:24:28Z | |
dc.date.issued | 2000 | |
dc.identifier.citation | Saw, S., Aw, T.-C. (2000). Age-related reference intervals for free and total prostate-specific antigen in a Singaporean population. Pathology 32 (4) : 245-249. ScholarBank@NUS Repository. | |
dc.identifier.issn | 00313025 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/129603 | |
dc.description.abstract | Cancer of the prostate is the sixth most frequently found cancer in Singapore. Prostate-specific antigen (PSA) is the most clinically useful tumour marker available today for the diagnosis and management of prostate cancer. To enhance the value of PSA as a screening test we developed age-specific intervals for our ethnic population. The measurement of free PSA was included in the study to calculate the free:total ratio which enhances the differential diagnosis of prostate cancer from benign prostatic hyperplasia or prostatitis. The total PSA upper limits of 10-year intervals, beginning at 30-years-old, were 1.4, 1.7, 2.3, 4.0, 6.3 and 6.6 μg/l. Free PSA cut-off limits were 0.4, 0.5, 0.5, 1.0, 1.5 and 1.6 μg/l. The free:total ratio of PSA was not age dependent. Abbott AxSym standardised their calibration material for both free and total PSA assays with the Stanford 90:10 reference material. This laboratory has implemented these age-specific reference intervals and are currently following up their pick-up rate in the detection of prostate cancer. | |
dc.source | Scopus | |
dc.subject | Age | |
dc.subject | AxSym | |
dc.subject | Prostate-specific antigen | |
dc.subject | Reference interval | |
dc.type | Article | |
dc.contributor.department | PATHOLOGY | |
dc.description.sourcetitle | Pathology | |
dc.description.volume | 32 | |
dc.description.issue | 4 | |
dc.description.page | 245-249 | |
dc.description.coden | PTLGA | |
dc.identifier.isiut | NOT_IN_WOS | |
Appears in Collections: | Staff Publications |
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