Please use this identifier to cite or link to this item:
|Title:||Effect of ondansetron pretreatment on pain after rocuronium and propofol injection: A randomised, double-blind controlled comparison with lidocaine||Authors:||Reddy, M.S.
|Keywords:||Anaesthetics, intravenous: propofol
Neuromuscular non-depolarising agents: rocuronium
|Issue Date:||2001||Citation:||Reddy, M.S., Chen, F.-G., Ng, H.-P. (2001). Effect of ondansetron pretreatment on pain after rocuronium and propofol injection: A randomised, double-blind controlled comparison with lidocaine. Anaesthesia 56 (9) : 902-905. ScholarBank@NUS Repository. https://doi.org/10.1046/j.1365-2044.2001.02059-6.x||Abstract:||In a randomised, controlled, double-blinded trial to study the effect of ondansetron pretreatment on the pain produced after intravenous injection of rocuronium and propofol in comparison with lidocaine, 60 patients were randomly assigned to one of three groups. Group 1 received 5 ml of intravenous 0.9% sodium chloride solution pretreatment, group 2 received ondansetron 4 mg (2 mg.ml -1 solution) diluted into a 5-ml solution, and group 3 received 50 mg lidocaine (5 ml 1% solution); this was followed 1 min later by rocuronium and propofol. Pain was reduced significantly in the ondansetron and lidocaine groups (p < 0.0001) compared with placebo, and significantly better with lidocaine than with ondansetron (p = 0.02). We conclude that ondansetron is effective in relieving the pain of rocuronium but is not as effective as lidocaine.||Source Title:||Anaesthesia||URI:||http://scholarbank.nus.edu.sg/handle/10635/129515||ISSN:||00032409||DOI:||10.1046/j.1365-2044.2001.02059-6.x|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Feb 11, 2020
WEB OF SCIENCETM
checked on Feb 4, 2020
checked on Feb 14, 2020
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.