Please use this identifier to cite or link to this item: https://doi.org/10.1098/rsif.2013.0676
DC FieldValue
dc.titleInvestigation of nerve injury through microfluidic devices
dc.contributor.authorSiddique, R.
dc.contributor.authorThakor, N.
dc.date.accessioned2016-10-19T08:43:55Z
dc.date.available2016-10-19T08:43:55Z
dc.date.issued2014-01-06
dc.identifier.citationSiddique, R., Thakor, N. (2014-01-06). Investigation of nerve injury through microfluidic devices. Journal of the Royal Society Interface 11 (90) : -. ScholarBank@NUS Repository. https://doi.org/10.1098/rsif.2013.0676
dc.identifier.issn17425689
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/128675
dc.description.abstractTraumatic injuries, both in the central nervous system (CNS) and peripheral nervous system (PNS), can potentially lead to irreversible damage resulting in permanent loss of function. Investigating the complex dynamics involved in these processes may elucidate the biological mechanisms of both nerve degeneration and regeneration, and may potentially lead to the development of new therapies for recovery. A scientific overview on the biological foundations of nerve injury is presented. Differences between nerve regeneration in the central and PNS are discussed. Advances in microtechnology over the past several years have led to the development of invaluable tools that now facilitate investigation of neurobiology at the cellular scale. Microfluidic devices are explored as a means to study nerve injury at the necessary simplification of the cellular level, including those devices aimed at both chemical and physical injury, as well as those that recreate the post-injury environment. © 2013 The Author(s) Published by the Royal Society. All rights reserved.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1098/rsif.2013.0676
dc.sourceScopus
dc.subjectMicrofluidic chamber
dc.subjectNerve regeneration
dc.subjectPeripheral nerve injury
dc.typeReview
dc.contributor.departmentELECTRICAL ENGINEERING
dc.description.doi10.1098/rsif.2013.0676
dc.description.sourcetitleJournal of the Royal Society Interface
dc.description.volume11
dc.description.issue90
dc.description.page-
dc.identifier.isiut000332384400001
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