Please use this identifier to cite or link to this item:
|Title:||Recent advances in understanding proteins involved in lipid droplet formation, growth and fusion||Authors:||Tan, J.S.Y.
|Issue Date:||20-May-2014||Citation:||Tan, J.S.Y., Seow, C.J.P., Goh, V.J., Silver, D.L. (2014-05-20). Recent advances in understanding proteins involved in lipid droplet formation, growth and fusion. Journal of Genetics and Genomics 41 (5) : 251-259. ScholarBank@NUS Repository. https://doi.org/10.1016/j.jgg.2014.03.003||Abstract:||Lipid droplets (LDs) were once viewed as simple, inert lipid micelles. However, they are now known to be organelles with a rich proteome involved in a myriad of cellular processes. LDs are heterogeneous in nature with different sizes and compositions of phospholipids, neutral lipids and proteins. This review takes a focused look at the roles of proteins involved in the regulation of LD formation, expansion, and morphology. The related proteins are summarized such as the fat-specific protein (Fsp27), fat storage-inducing transmembrane (FIT) proteins, seipin and ADP-ribosylation factor 1-coat protein complex I (Arf-COPI). Finally, we present important challenges in LD biology for a deeper understanding of this dynamic organelle to be achieved. © 2014.||Source Title:||Journal of Genetics and Genomics||URI:||http://scholarbank.nus.edu.sg/handle/10635/128660||ISSN:||18735533||DOI:||10.1016/j.jgg.2014.03.003|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.