Please use this identifier to cite or link to this item: https://doi.org/10.5665/sleep.3302
Title: Sustained attention performance during sleep deprivation associates with instability in behavior and physiologic measures at baseline
Authors: Chua, E.C.-P.
Yeo, S.-C.
Lee, I.T.-G. 
Tan, L.-C.
Lau, P. 
Cai, S. 
Zhang, X. 
Puvanendran, K. 
Gooley, J.J. 
Keywords: Instability
Inter-individual differences
Psychomotor vigilance
Sleep deprivation
Variability
Issue Date: 1-Jan-2014
Citation: Chua, E.C.-P., Yeo, S.-C., Lee, I.T.-G., Tan, L.-C., Lau, P., Cai, S., Zhang, X., Puvanendran, K., Gooley, J.J. (2014-01-01). Sustained attention performance during sleep deprivation associates with instability in behavior and physiologic measures at baseline. Sleep 37 (1) : 27-39. ScholarBank@NUS Repository. https://doi.org/10.5665/sleep.3302
Abstract: Study Objectives: To identify baseline behavioral and physiologic markers that associate with individual differences in sustained attention during sleep deprivation. Design: In a retrospective study, ocular, electrocardiogram, and electroencephalogram (EEG) measures were compared in subjects who were characterized as resilient (n = 15) or vulnerable (n = 15) to the effects of total sleep deprivation on sustained attention. Setting: Chronobiology and Sleep Laboratory, Duke-NUS Graduate Medical School Singapore. Participants: Healthy volunteers aged 22-32 years from the general population. Interventions: Subjects were kept awake for at least 26 hours under constant environmental conditions. Every 2 hours, sustained attention was assessed using a 10-minute psychomotor vigilance task (PVT). Measurements and Results: During baseline sleep and recovery sleep, EEG slow wave activity was similar in resilient versus vulnerable subjects, suggesting that individual differences in vulnerability to sleep loss were not related to differences in homeostatic sleep regulation. Rather, irrespective of time elapsed since wake, subjects who were vulnerable to sleep deprivation exhibited slower and more variable PVT response times, lower and more variable heart rate, and higher and more variable EEG spectral power in the theta frequency band (6.0-7.5 Hz). Conclusions: Performance decrements in sustained attention during sleep deprivation associate with instability in behavioral and physiologic measures at baseline. Small individual differences in sustained attention that are present at baseline are amplified during prolonged wakefulness, thus contributing to large between-subjects differences in performance and sleepiness.
Source Title: Sleep
URI: http://scholarbank.nus.edu.sg/handle/10635/128614
ISSN: 01618105
DOI: 10.5665/sleep.3302
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

23
checked on Sep 17, 2019

WEB OF SCIENCETM
Citations

22
checked on Sep 17, 2019

Page view(s)

397
checked on Sep 20, 2019

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.