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Title: MRI and PET-CT in the diagnosis and follow-up of a lymphoma case with multifocal peripheral nerve involvement
Authors: Agrawal, S.
Gi, M.T.
Ng, S.B. 
Puhaindran, M.E.
Singhania, P.
Issue Date: Jan-2013
Citation: Agrawal, S., Gi, M.T., Ng, S.B., Puhaindran, M.E., Singhania, P. (2013-01). MRI and PET-CT in the diagnosis and follow-up of a lymphoma case with multifocal peripheral nerve involvement. Diagnostic and Interventional Radiology 19 (1) : 25-28. ScholarBank@NUS Repository.
Abstract: Lymphoma of the peripheral nerve, particularly of the T-cell variety, is an extremely rare subtype of extra nodal lymphoma that has a variable response to current therapeutic regimens. Here, we present a patient with natural killer (NK)/T-cell lymphoma in remission who presented with a two-month history of right forearm swelling and paresthesia in the ulnar nerve distribution. Magnetic resonance imaging (MRI) showed an ulnar nerve mass identified as a nerve sheath tumor. Frozen section and postresection biopsies showed an Epstein-Barr virus-positive NK/T-cell lymphoma, nasal type. Consequently, the patient received chemotherapy following resection. Four months later, the patient developed a proximal leg mass, which was diagnosed as tibial nerve lymphoma. The patient was then treated with chemotherapy and follow-up was done by positron emission tomography-computed tomography (PET-CT). In conclusion, lymphoma should be considered in the differential diagnosis of a peripheral nerve mass. MRI is a useful imaging tool together with PET-CT, which plays a beneficial role in the follow-up of these patients on therapy as well as diagnosis of new lesions. © Turkish Society of Radiology 2013.
Source Title: Diagnostic and Interventional Radiology
ISSN: 13053825
DOI: 10.4261/1305-3825.DIR.5876-12.1
Appears in Collections:Staff Publications

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