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Title: High burden of antimicrobial drug resistance in Asia
Authors: Lai, C.-C.
Lee, K.
Xiao, Y.
Ahmad, N.
Veeraraghavan, B.
Thamlikitkul, V.
Tambyah, P.A. 
Nelwan, R.H.H.
Shibl, A.M.
Wu, J.-J.
Seto, W.-H.
Hsueh, P.-R.
Keywords: Antimicrobial resistance
Carbapenem-resistant Enterobacteriaceae
Meticillin-resistant Staphylococcus aureus
Vancomycin-resistant enterococci
Issue Date: 2014
Citation: Lai, C.-C., Lee, K., Xiao, Y., Ahmad, N., Veeraraghavan, B., Thamlikitkul, V., Tambyah, P.A., Nelwan, R.H.H., Shibl, A.M., Wu, J.-J., Seto, W.-H., Hsueh, P.-R. (2014). High burden of antimicrobial drug resistance in Asia. Journal of Global Antimicrobial Resistance. ScholarBank@NUS Repository.
Abstract: The rapid development of antimicrobial resistance among micro-organisms is a serious public health concern. Moreover, the dissemination of antibiotic-resistant bacteria makes this issue a global problem, and Asia is no exception. For example, since New Delhi metallo-β-lactamase (NDM)-producing Enterobacteriaceae were identified in India, further spread of NDM has become a worldwide threat. However, the epidemiology of antibiotic-resistant bacteria in Asia may be different to other regions, and clinical condition may be worse than in western countries. Antibiotic-resistant bacteria, including community-acquired and hospital-acquired meticillin-resistant Staphylococcus aureus (MRSA), vancomycin-intermediate S. aureus (VISA), vancomycin-resistant enterococci, macrolide- and penicillin-resistant Streptococcus pneumoniae, extend-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae, carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa and Acinetobacter spp., are becoming prevalent in many countries in Asia. Moreover, the prevalence of each antibiotic-resistant bacterium in each country is not identical. This review provides useful information regarding the critical condition of antibiotic resistance in Asia and emphasises the importance of continuous surveillance of resistance data. © 2014 International Society for Chemotherapy of Infection and Cancer.
Source Title: Journal of Global Antimicrobial Resistance
ISSN: 22137165
DOI: 10.1016/j.jgar.2014.02.007
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