Please use this identifier to cite or link to this item: https://doi.org/10.1038/oncsis.2013.10
Title: Overexpression of miR-26a-2 in human liposarcoma is correlated with poor patient survival
Authors: Lee, D.H.
Amanat, S.
Goff, C.
Weiss, L.M.
Said, J.W.
Doan, N.B.
Sato-Otsubo, A.
Ogawa, S.
Forscher, C.
Koeffler, H.P. 
Keywords: Apoptosis
Liposarcoma
Microrna
RCBTB1
SNP array
Survival
Issue Date: 2013
Citation: Lee, D.H., Amanat, S., Goff, C., Weiss, L.M., Said, J.W., Doan, N.B., Sato-Otsubo, A., Ogawa, S., Forscher, C., Koeffler, H.P. (2013). Overexpression of miR-26a-2 in human liposarcoma is correlated with poor patient survival. Oncogenesis 2 : -. ScholarBank@NUS Repository. https://doi.org/10.1038/oncsis.2013.10
Abstract: Approximately 90% of well-differentiated/de-differentiated liposarcomas (WDLPS/DDLPS), the most common LPS subtype, have chromosomal amplification at 12q13-q22. Many protein-coding genes in the region, such as MDM2 and , have been studied as potential therapeutic targets for LPS treatment, with minimal success. In the amplified region near the MDM2 gene, our single nucleotide polymorphism (SNP) array analysis of 75 LPS samples identified frequent amplification of miR-26a-2. Besides being in the amplicon, miR-26a-2 was overexpressed significantly in WDLPS/DDLPS (P
Source Title: Oncogenesis
URI: http://scholarbank.nus.edu.sg/handle/10635/126833
ISSN: 21579024
DOI: 10.1038/oncsis.2013.10
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