Please use this identifier to cite or link to this item: https://doi.org/10.1093/tropej/fmr108
Title: N-acetylcysteine in children with dengue-associated liver failure: A case report
Authors: Lim, G.
Lee, J.H. 
Keywords: Dengue
Liver failure
N-acetylcysteine
Paediatric
Issue Date: Oct-2012
Citation: Lim, G., Lee, J.H. (2012-10). N-acetylcysteine in children with dengue-associated liver failure: A case report. Journal of Tropical Pediatrics 58 (5) : 409-413. ScholarBank@NUS Repository. https://doi.org/10.1093/tropej/fmr108
Abstract: There is no specific treatment for dengue-associated fulminant liver failure. We report a child with dengue-associated fulminant liver failure who was treated successfully with intravenous N-acetylcysteine. A 6-year-old boy was diagnosed with dengue-associated fulminant liver failure. After administration of intravenous N-acetylcysteine, a rapid decrease in liver transaminases and normalization of coagulation profile was observed followed by clinical improvement and favourable outcome despite factors associated with poor prognosis. The use of intravenous N-acetylcysteine is safe and efficient in the treatment of dengue-associated fulminant liver failure, especially in centres when liver transplantation is not readily available. © The Author [2011]. Published by Oxford University Press. All rights reserved.
Source Title: Journal of Tropical Pediatrics
URI: http://scholarbank.nus.edu.sg/handle/10635/126521
ISSN: 01426338
DOI: 10.1093/tropej/fmr108
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