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Title: Genetic analysis
Authors: Smith, G.J.D. 
Bahl, J. 
Vijaykrishna, D. 
Keywords: Bayesian inference
Maximum likelihood
Natural selection
Neighbor joining
Sequence alignment
Issue Date: 2012
Abstract: Genetic analysis of sequence data is central to determining the evolutionary history and molecular epidemiology of viruses, particularly those such as influenza A virus that have complex ecosystems involving multiple hosts. Here we provide an outline of routine phylogenetic analyses of influenza A viruses including multiple sequence alignment, selecting the best-fit evolutionary model and phylogenetic tree reconstruction using Neighbor joining, Maximum likelihood, and Bayesian inference. © 2012 Springer Science+Business Media, LLC.
Source Title: Methods in Molecular Biology
ISBN: 9781617796203
ISSN: 10643745
DOI: 10.1007/978-1-61779-621-0_13
Appears in Collections:Staff Publications

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