Please use this identifier to cite or link to this item: https://doi.org/10.1007/s12105-013-0465-9
Title: Sclerosing Polycystic Adenosis of Salivary Glands: A Review with Some Emphasis on Intraductal Epithelial Proliferations
Authors: Petersson, F. 
Keywords: Adenosis
Carcinoma
Dysplasia
Hyperplasia
Salivary gland
Sclerosing polycystic adenosis
Issue Date: 2013
Citation: Petersson, F. (2013). Sclerosing Polycystic Adenosis of Salivary Glands: A Review with Some Emphasis on Intraductal Epithelial Proliferations. Head and Neck Pathology 7 (SUPPL 1) : 97-106. ScholarBank@NUS Repository. https://doi.org/10.1007/s12105-013-0465-9
Abstract: Sclerosing polycystic adenosis (SPA) is a rare condition of salivary glands. The most common site is the parotid gland (80 % of cases). SPA shows no gender predilection and occurs over a wide age spectrum (9-84 years). SPA is mostly unifocal, but may rarely be multifocal. Histologically, SPA are sharply circumscribed mostly unencapsulated lesions composed of acinar and ductal components with variable cytomorphological characteristics, including foamy, vacuolated, apocrine, mucous, clear/ballooned, squamous, columnar and oncocyte-like cells. Characteristic for SPA is the presence of large acinar cells with abundant eosinophilic cytoplasmic granules. The stroma is densely collagenized, frequently harbouring a variably intense chronic inflammatory infiltrate and may contain fat. Rarely the stroma is myxoid. Some degree of intraductal epithelial proliferations have been reported in at least 50 % of cases. The proportion of cases with epithelial proliferations that fulfill criteria for high-grade ductal carcinoma in-situ is
Source Title: Head and Neck Pathology
URI: http://scholarbank.nus.edu.sg/handle/10635/125891
ISSN: 1936055X
DOI: 10.1007/s12105-013-0465-9
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

17
checked on Aug 3, 2020

WEB OF SCIENCETM
Citations

16
checked on Aug 3, 2020

Page view(s)

48
checked on Jul 31, 2020

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.