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Title: Viral Hemorrhagic Fevers
Authors: Wilder-Smith, A. 
Keywords: Arenavirus
Crimean-Congo hemorrhagic fever viruses
Ebola virus
Hanta pulmonary syndrome
Hantavirus infections
Hemorrhagic fever with pulmonary syndrome
Lassa fever
Marburg virus
Rift Valley fever
Viral hemorrhagic fever
Issue Date: 15-Jan-2010
Abstract: Viral hemorrhagic fevers (VHF) are a group of febrile illnesses caused by several distinct families of viruses that share a number of properties (small RNA genome, lipid envelope, zoonotic natural cycle, febrile illness with minor to major hemorrhagic manifestations) but differ in others (replication strategy, natural cycle, pathogenesis, and mode of transmission). These groups include the arena-, bunya-, filo-, and flaviviruses. The families of viruses that cause viral hemorrhagic fevers are distributed widely. Each virus is associated with one or more nonhuman host or vector species, which determine the geographical distribution. Rodents are the main reservoir for hantavirus infections, hemorrhagic fever with renal syndrome, and Lassa fever. Aedes mosquitoes are the vectors for rift valley fever and ticks for Crimean-Congo hemorrhagic fever. The VHF viruses usually are transmitted to humans where the habitats of infected reservoir hosts or vectors and of humans overlap. In general, travelers are rarely affected, and humans are incidental, dead-end hosts for these enzootic diseases. © 2009 Blackwell Publishing.
Source Title: Tropical Diseases in Travelers
ISBN: 9781405184410
DOI: 10.1002/9781444316841.ch13
Appears in Collections:Staff Publications

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