Please use this identifier to cite or link to this item: https://doi.org/10.1166/jmihi.2012.1119
Title: Feature selection for computer-aided angle closure glaucoma mechanism detection
Authors: Wirawan, A.
Kwoh, C.K.
Chew, P.T.K. 
Aquino, M.C.D.
Loon, S.C.
See, J.
Zheng, C.
Lin, W.
Keywords: Angle closure glaucoma
Computer aided detection
Feature selection
Machine learning
Issue Date: Dec-2012
Citation: Wirawan, A., Kwoh, C.K., Chew, P.T.K., Aquino, M.C.D., Loon, S.C., See, J., Zheng, C., Lin, W. (2012-12). Feature selection for computer-aided angle closure glaucoma mechanism detection. Journal of Medical Imaging and Health Informatics 2 (4) : 438-444. ScholarBank@NUS Repository. https://doi.org/10.1166/jmihi.2012.1119
Abstract: Selection of relevant features is of fundamental importance in building robust classifiers for computer-aided detection (CAD) of angle closure glaucoma mechanism. Typically one is interested in determining which, of a large number of potentially redundant or noisy features, are most discriminative for classification. The objective of the paper is to exploit machine learning algorithms for automated classification of different angle closure mechanisms based on the quantitative assessment of Anterior Segment Optical Coherence Tomography (AS-OCT). In this paper, we propose an effective combination of Minimum Redundancy Maximum Relevance (MRMR), a mutual information feature selection, with AdaBoost, an adaptive boosting to detect angle closure glaucoma. The proposed method effectively combines the best feature selection and classifier to the problem. A sequential forward search was conducted to determine the optimal feature subset by the proposed criteria. The optimal selected feature subset, using only 11.90% of the entire available feature, for our angle closure glaucoma dataset outperforms the result using all 84 features. It also achieves better prediction compared to 4 other methods, i.e., Classification Tree, Support Vector Machine (SVM), Random Forest and Naïve Bayes. The reduced set of features avoids computation of unnecessary features and thus improves the efficiency. Furthermore, 9 out of the 10 selected features have been clinically proven to be important in determining the type of angle closure glaucoma. The algorithm show promising and encouraging results to detect and determine the type of angle closure glaucoma which may help early recognition and treatment of the disease. The reduced complexity of the generated models achieves better generalization and improves the efficiency. Copyright © 2012 American Scientific Publishers. All rights reserved.
Source Title: Journal of Medical Imaging and Health Informatics
URI: http://scholarbank.nus.edu.sg/handle/10635/125718
ISSN: 21567018
DOI: 10.1166/jmihi.2012.1119
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

9
checked on Jun 7, 2021

WEB OF SCIENCETM
Citations

8
checked on Jun 7, 2021

Page view(s)

115
checked on Jun 6, 2021

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.