Please use this identifier to cite or link to this item: https://doi.org/10.1002/pbc.23382
Title: Diagnostic delay in pediatric solid tumors: A population based study on determinants and impact on outcomes
Authors: Loh, A.H.P.
Aung, L.
Ha, C.
Tan, A.-M.
Quah, T.C. 
Chui, C.-H.
Keywords: Childhood cancer registry
Diagnostic delay
Lag time
Prognostic factors
Solid tumors
Tumor biology
Issue Date: Apr-2012
Citation: Loh, A.H.P., Aung, L., Ha, C., Tan, A.-M., Quah, T.C., Chui, C.-H. (2012-04). Diagnostic delay in pediatric solid tumors: A population based study on determinants and impact on outcomes. Pediatric Blood and Cancer 58 (4) : 561-565. ScholarBank@NUS Repository. https://doi.org/10.1002/pbc.23382
Abstract: Background: Despite socioeconomic and clinical progress, pediatric tumors continue to present in advanced stage, and may be due to delays in diagnosis. This study aimed to identify factors associated with diagnostic delay (time between symptom onset and diagnosis) in pediatric tumors in a population-based study, and to assess the impact of delay on subsequent outcome. Procedure: Natural logarithm of delay was retrospectively described for 390 newly diagnosed tumors reported to the Singapore Childhood Cancer Registry from 1997 to 2007. Delay was correlated with socio-demographic, disease and healthcare-system factors using multivariate linear regression, and with event-free survival (EFS) using Cox regression analysis. Results: Total median delay was 5.3 weeks (range 0.1-283.1). Shorter delay was independently associated with younger patient age (P=0.006), abdominal and pelvic sites (P
Source Title: Pediatric Blood and Cancer
URI: http://scholarbank.nus.edu.sg/handle/10635/125601
ISSN: 15455009
DOI: 10.1002/pbc.23382
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