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Title: Asthma syndrome understanding asthma phenotypes in children
Authors: Mahesh Babu, R. 
Kinimi, I.
Keywords: Childhood asthma
Issue Date: Jul-2012
Abstract: Since the first National heart, blood, lung institute (NHBLI)-Asthma Management guidelines (1991), the international recommendations have been to diagnose asthma with a set of clinical parameters, and treat with a standardized approach. However, practicing physicians, encounter children who continue to have symptoms despite adequate and appropriate therapy. Asthma is not a single disease, but a common manifestation of many overlapping individual diseases or phenotypes - each characterized by its own genetic and environmental interaction. Hence asthma is now classified as phenotypes. So, does phenotype represent superficial groups of asthmatic children with similar set of signs and symptoms or does it actually represent fundamentally separate disease entities?
Source Title: Indian Journal of Practical Pediatrics
ISSN: 09729607
Appears in Collections:Staff Publications

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