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Title: The MicroFlow Spacer: A Drug-Eluting Stent for the Ethmoid Sinus
Authors: Catalano, P.J.
Thong, M. 
Weiss, R.
Rimash, T.
Keywords: Drug
Issue Date: Jul-2011
Citation: Catalano, P.J., Thong, M., Weiss, R., Rimash, T. (2011-07). The MicroFlow Spacer: A Drug-Eluting Stent for the Ethmoid Sinus. Indian Journal of Otolaryngology and Head and Neck Surgery 63 (3) : 279-284. ScholarBank@NUS Repository.
Abstract: To evaluate the short-term outcomes and safety of a newly introduced drug-eluting ethmoid stent. Prospective study of 23 patients with a total of 40 implanted ethmoid sinuses. Two tertiary care medical facility. Twenty-three patients with medically refractory chronic rhinosinusitis were treated with patient-appropriate endoscopic sinus surgery, with the modification of treating the ethmoid sinuses with an ethmoid stent infused with triamcinolone, instead of conventional endoscopic ethmoidectomy. Patients were then followed up over 6 months. Outcomes were assessed by interval changes in 20-item Sino-Nasal Outcome Test (SNOT-20) and Lund-MacKay CT scores. Safety was determined by adverse events. Overall, the pre-op SNOT-20 mean score was 2. 18, versus post-op score of 1. 02, an improvement of 1. 16 that was both statistically (P < 0. 001) and clinically significant. Ethmoid-specific and side-specific Lund-MacKay mean scores both also showed statistically significant improvements. Pre-op ethmoid-specific Lund-MacKay mean score was 1. 93, versus post-op score of 1. 10, an improvement of 0. 83 (P < 0. 001). Pre-op side-specific Lund-MacKay mean score was 5. 75, compared with post-op score of 2. 95, an improvement of 2. 80 (P < 0. 001). There were no significant intra-op or post-op complications encountered. This triamcinolone-infused ethmoid stent appears safe and effective in treating chronic ethmoid sinus disease within the defined follow-up period. The ability to deliver medication directly to diseased mucosa holds wide-ranging potential. © 2011 Association of Otolaryngologists of India.
Source Title: Indian Journal of Otolaryngology and Head and Neck Surgery
ISSN: 22313796
DOI: 10.1007/s12070-011-0258-y
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