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https://doi.org/10.1007/s10633-012-9368-4
DC Field | Value | |
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dc.title | Full-field electroretinography under general anesthesia in retinoblastoma | |
dc.contributor.author | Sachidanandam, R. | |
dc.contributor.author | Krishnakumar, S. | |
dc.contributor.author | Gopal, L. | |
dc.contributor.author | O'Brien, J.M. | |
dc.contributor.author | Khetan, V. | |
dc.contributor.author | Sen, P. | |
dc.date.accessioned | 2016-07-08T09:28:31Z | |
dc.date.available | 2016-07-08T09:28:31Z | |
dc.date.issued | 2013-04 | |
dc.identifier.citation | Sachidanandam, R., Krishnakumar, S., Gopal, L., O'Brien, J.M., Khetan, V., Sen, P. (2013-04). Full-field electroretinography under general anesthesia in retinoblastoma. Documenta Ophthalmologica 126 (2) : 149-157. ScholarBank@NUS Repository. https://doi.org/10.1007/s10633-012-9368-4 | |
dc.identifier.issn | 00124486 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/125549 | |
dc.description.abstract | Purpose: To investigate the electrical responses of the retina in retinoblastoma (RB), by recording full-field electroretinography (ERG) under general anesthesia. Methods: The ERG was recorded using Ephios hand-held portable ERG system, according to International Standards for Clinical Electrophysiology of Vision. Forty-eight eyes of 43 cases and 33 eyes of 33 controls were enrolled. The cases were classified based on international intraocular retinoblastoma classification (IIRC). Forty-eight eyes of cases were divided into 30 cases with active RB and 18 cases with regressed RB. Results: The amplitudes of a- and b-waves were decreased as compared to controls in all subgroups. The implicit times of all RB patients from group A to C differed statistically from controls (p value < 0.05) except for single-flash rod response. The ERG waveforms in group E eyes were non-recordable. The comparison of ERG parameters between active and regressed groups (IIRC groups A and B) was statistically insignificant. Single case follow-up of unilateral RB after systemic chemotherapy showed improvement in amplitudes compared to baseline parameters. Conclusions: Reduced amplitudes and delayed implicit times were noted in advanced disease. The ERG of RB cases did not follow any specific pattern of waveform. ERG appears to be a dynamic parameter to observe changes following treatment for RB. Although ERG is not a diagnostic test for RB, it can be used as a complementary test to assess the residual retinal function in RB eyes. © 2013 Springer-Verlag Berlin Heidelberg. | |
dc.description.uri | http://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1007/s10633-012-9368-4 | |
dc.source | Scopus | |
dc.subject | Full-field electroretinography | |
dc.subject | General anesthesia | |
dc.subject | Hand-held ERG | |
dc.subject | International intraocular retinoblastoma classification | |
dc.subject | Retinoblastoma | |
dc.type | Article | |
dc.contributor.department | OPHTHALMOLOGY | |
dc.description.doi | 10.1007/s10633-012-9368-4 | |
dc.description.sourcetitle | Documenta Ophthalmologica | |
dc.description.volume | 126 | |
dc.description.issue | 2 | |
dc.description.page | 149-157 | |
dc.description.coden | DOOPA | |
dc.identifier.isiut | 000317079300008 | |
Appears in Collections: | Staff Publications |
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