Please use this identifier to cite or link to this item: https://doi.org/10.1161/STROKEAHA.113.001576
Title: Reduction in early stroke risk in carotid stenosis with transient ischemic attack associated with statin treatment
Authors: Merwick, Á.
Albers, G.W.
Arsava, E.M.
Ay, H.
Calvet, D.
Coutts, S.B.
Cucchiara, B.L.
Demchuk, A.M.
Giles, M.F.
Mas, J.-L.
Olivot, J.M.
Purroy, F.
Rothwell, P.M.
Saver, J.L.
Sharma, V.K. 
Tsivgoulis, G.
Kelly, P.J.
Keywords: Carotid stenosis
Ischemic attack
Statin
Transient
Issue Date: Oct-2013
Citation: Merwick, Á., Albers, G.W., Arsava, E.M., Ay, H., Calvet, D., Coutts, S.B., Cucchiara, B.L., Demchuk, A.M., Giles, M.F., Mas, J.-L., Olivot, J.M., Purroy, F., Rothwell, P.M., Saver, J.L., Sharma, V.K., Tsivgoulis, G., Kelly, P.J. (2013-10). Reduction in early stroke risk in carotid stenosis with transient ischemic attack associated with statin treatment. Stroke 44 (10) : 2814-2820. ScholarBank@NUS Repository. https://doi.org/10.1161/STROKEAHA.113.001576
Abstract: Background and Purpose-Statins reduce stroke risk when initiated months after transient ischemic attack (TIA)/stroke and reduce early vascular events in acute coronary syndromes, possibly via pleiotropic plaque stabilization. Few data exist on acute statin use in TIA. We aimed to determine whether statin pretreatment at TIA onset modified early stroke risk in carotid stenosis. Methods-We analyzed data from 2770 patients with TIA from 11 centers, 387 with ipsilateral carotid stenosis. ABCD2 score, abnormal diffusion weighted imaging, medication pretreatment, and early stroke were recorded. Results-In patients with carotid stenosis, 7-day stroke risk was 8.3% (95% confidence interval [CI], 5.7-11.1) compared with 2.7% (CI, 2.0%-3.4%) without stenosis (P
Source Title: Stroke
URI: http://scholarbank.nus.edu.sg/handle/10635/125446
ISSN: 00392499
DOI: 10.1161/STROKEAHA.113.001576
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