Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/125238
DC FieldValue
dc.titleNUMERICAL STUDY OF ERYTHROCYTE MECHANICS: DEFORMATION AND AGGREGATION
dc.contributor.authorMAUNG YE SWE SOE
dc.date.accessioned2016-06-30T18:01:22Z
dc.date.available2016-06-30T18:01:22Z
dc.date.issued2016-01-19
dc.identifier.citationMAUNG YE SWE SOE (2016-01-19). NUMERICAL STUDY OF ERYTHROCYTE MECHANICS: DEFORMATION AND AGGREGATION. ScholarBank@NUS Repository.
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/125238
dc.description.abstractViscoelasticity of the RBC membrane has been known to material scientists and biologists since the 1970s, yet present-day numerical models of RBCs in microvascular flows still model the RBC deformation dynamics without any viscous component. Models of RBC aggregation routinely employ attraction ranges that are twenty times larger than intercellular distances specified by depletion and bridging theory, despite the fact that these distances have been verified with transmission electron microscopy. These poor approaches to RBC modeling prevent numerical models from being employed as clinical tools for addressing RBC pathologies. In this thesis work, I demonstrate the physiological baselines of RBC deformation and aggregation behavior, achievable with correct membrane viscosity and aggregation distance considerations. Using the computational models developed in this thesis, the shift in RBC functional behavior due to property change may be assessed and this will assist in designing strategies to reverse RBC related disorders.
dc.language.isoen
dc.subjectred blood cell, viscoelasticity, aggregation, hemodynamics, bifurcation, spectrin
dc.typeThesis
dc.contributor.departmentBIOMEDICAL ENGINEERING
dc.contributor.supervisorKIM SANGHO
dc.description.degreePh.D
dc.description.degreeconferredDOCTOR OF PHILOSOPHY
dc.identifier.isiutNOT_IN_WOS
Appears in Collections:Ph.D Theses (Open)

Show simple item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
PSR170.avi14.96 MBAVI

OPEN

None Preview online
0_1Hz.avi5.66 MBAVI

OPEN

None Preview online
50_Hz.avi20.21 MBAVI

OPEN

None Preview online
0_3umPerSecShear.avi6.36 MBAVI

OPEN

None Preview online
R490VSR30Slide.avi10.6 MBAVI

OPEN

None Preview online
MaungYeSS.pdf11.88 MBAdobe PDF

OPEN

NoneView/Download

Page view(s)

146
checked on Nov 18, 2021

Download(s)

234
checked on Nov 18, 2021

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.