Please use this identifier to cite or link to this item: https://doi.org/10.4161/gmic.28681
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dc.titleMetabolic tinkering by the gut microbiome: Implications for brain development and function
dc.contributor.authorSelkrig, J.
dc.contributor.authorWong, P.
dc.contributor.authorZhang, X.
dc.contributor.authorPettersson, S.
dc.date.accessioned2016-06-01T10:32:33Z
dc.date.available2016-06-01T10:32:33Z
dc.date.issued2014-03-31
dc.identifier.citationSelkrig, J., Wong, P., Zhang, X., Pettersson, S. (2014-03-31). Metabolic tinkering by the gut microbiome: Implications for brain development and function. Gut Microbes 5 (3) : -. ScholarBank@NUS Repository. https://doi.org/10.4161/gmic.28681
dc.identifier.issn19490984
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/124870
dc.description.abstractBrain development is an energy demanding process that relies heavily upon diet derived nutrients. Gut microbiota enhance the host's ability to extract otherwise inaccessible energy from the diet via fermentation of complex oligosaccharides in the colon. This nutrient yield is estimated to contribute up to 10% of the host's daily caloric requirement in humans and fluctuates in response to environmental variations. Research over the past decade has demonstrated a surprising role for the gut microbiome in normal brain development and function. In this review we postulate that perturbations in the gut microbial-derived nutrient supply, driven by environmental variation, profoundly impacts upon normal brain development and function. © 2014 Landes Bioscience.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.4161/gmic.28681
dc.sourceScopus
dc.subjectGlucose
dc.subjectGut microbiota
dc.subjectHypothalamic-pituitary-adrenal axis
dc.subjectMetabolism
dc.subjectMicrobiota-gut-brain axis
dc.subjectNeurodevelopment
dc.subjectShort chain fatty acids
dc.subjectβ-hydroxybutyrate
dc.typeReview
dc.contributor.departmentDUKE-NUS GRADUATE MEDICAL SCHOOL S'PORE
dc.description.doi10.4161/gmic.28681
dc.description.sourcetitleGut Microbes
dc.description.volume5
dc.description.issue3
dc.description.page-
dc.identifier.isiut000457429800018
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