Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.ophtha.2013.08.033
Title: Prognostic factor analysis of vitrectomy for retinal detachment associated with myopic macular holes
Authors: Lim, L.S.
Tsai, A.
Wong, D.
Wong, E.
Yeo, I. 
Loh, B.K.
Ang, C.L.
Ong, S.G.
Lee, S.Y. 
Issue Date: Jan-2014
Citation: Lim, L.S., Tsai, A., Wong, D., Wong, E., Yeo, I., Loh, B.K., Ang, C.L., Ong, S.G., Lee, S.Y. (2014-01). Prognostic factor analysis of vitrectomy for retinal detachment associated with myopic macular holes. Ophthalmology 121 (1) : 305-310. ScholarBank@NUS Repository. https://doi.org/10.1016/j.ophtha.2013.08.033
Abstract: Purpose To describe the anatomic and functional outcomes in a cohort of subjects undergoing vitrectomy for retinal detachment (RD) resulting from myopic macular hole (MH) and to analyze the prognostic and surgical factors predicting retinal reattachment and MH closure. Design Retrospective case series. Participants All patients who underwent vitrectomy for RD resulting from myopic MH between 2000 and 2009 at our center. Methods Case records were reviewed at 6 months after surgery. Retinal reattachment and complete anatomic success, defined as retinal reattachment with MH closure, were assessed. Multivariate logistic regression models, including age, gender, duration of symptoms, spherical equivalent refraction (SE), internal limiting membrane peeling, tamponade choice, and concurrent scleral buckling, were constructed to assess associations with covariates. Main Outcome Measures Retinal reattachment and complete anatomic success (retinal reattachment with MH closure). Results In total, 114 subjects were analyzed. Most were women (n = 79 [69.3%]), and the mean age was 57.5±13.3 years. The mean SE was -9.88±6.37 diopters. At 6 months, 98 subjects (86.0%) demonstrated retinal reattachment, of whom 93 subjects required only 1 operation. Complete anatomic success was achieved in 61 subjects (53.5%), of whom 55 needed only 1 operation. Subjects with retinal reattachment had better best-corrected visual acuity (BCVA; mean BCVA, 1.22±0.81 logarithm of the minimum angle of resolution [logMAR] units) than those without (mean BCVA, 1.98±1.26 logMAR units; P < 0.001), and subjects with complete anatomic success had better BCVA (mean BCVA, 1.05±0.87 logMAR units) than those without (mean BCVA, 1.62±0.87 logMAR units; P < 0.001). In multivariate analyses, increasing age and the use of perfluoropropane (C3F8) tamponade were predictive of anatomic success (per 1-year increase: odds ratio [OR], 1.049; 95% confidence interval [CI], 1.002-1.099; P = 0.04; and for tamponade: OR, 10.71; 95% CI, 1.08-106.29; P = 0.04). Conclusions Vitrectomy is effective in the repair of RD resulting from MH in myopic eyes, with retinal reattachment achieved more frequently than MH closure. Retinal reattachment and MH closure are important for improving visual outcomes. Greater age at presentation and use of C 3F8 are associated with a greater likelihood of anatomic success. © 2014 by the American Academy of Ophthalmology.
Source Title: Ophthalmology
URI: http://scholarbank.nus.edu.sg/handle/10635/124772
ISSN: 01616420
DOI: 10.1016/j.ophtha.2013.08.033
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