Please use this identifier to cite or link to this item: https://doi.org/10.1093/humrep/det420
Title: First pregnancy and live birth resulting from cryopreserved embryos obtained from in vitro matured oocytes after oophorectomy in an ovarian cancer patient
Authors: Prasath, E.B.
Chan, M.L.H.
Wong, W.H.W.
Lim, C.J.W.
Tharmalingam, M.D.
Hendricks, M.
Loh, S.F. 
Chia, Y.N.
Keywords: Cryopreservation
Fertility preservation
In vitro maturation
IVF
Ovarian cancer
Issue Date: Feb-2014
Citation: Prasath, E.B., Chan, M.L.H., Wong, W.H.W., Lim, C.J.W., Tharmalingam, M.D., Hendricks, M., Loh, S.F., Chia, Y.N. (2014-02). First pregnancy and live birth resulting from cryopreserved embryos obtained from in vitro matured oocytes after oophorectomy in an ovarian cancer patient. Human Reproduction 29 (2) : 276-278. ScholarBank@NUS Repository. https://doi.org/10.1093/humrep/det420
Abstract: In vitro maturation (IVM) of immature oocytes retrieved from surgically resected ovaries has been proposed as a method of fertility preservation in ovarian cancer patients undergoing definitive surgery. While there had been several reports of successful derivation of mature oocytes and or embryos, there have been no reports as yet of successful pregnancies. In this case report, we present a pregnancy and live birth from a young patient, with stage IIIC ovarian cancer, who had undergone fertility sparing surgery. The immature oocytes recovered after oophorectomy were fertilized after IVM. The embryos obtained were cryopreserved and later transferred to achieve a singleton healthy pregnancy leading to a live birth. © The Author 2013. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved.
Source Title: Human Reproduction
URI: http://scholarbank.nus.edu.sg/handle/10635/124716
ISSN: 02681161
DOI: 10.1093/humrep/det420
Appears in Collections:Staff Publications

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