Please use this identifier to cite or link to this item:
https://scholarbank.nus.edu.sg/handle/10635/124630
DC Field | Value | |
---|---|---|
dc.title | Multiple indomethacin-induced colonic perforations in an adolescent | |
dc.contributor.author | Loh, A.H.P. | |
dc.contributor.author | Ong, L.Y. | |
dc.contributor.author | Liew, W.K. | |
dc.contributor.author | Arkachaisri, T. | |
dc.contributor.author | Lee, V.K.M. | |
dc.contributor.author | Narasimhan, K.L. | |
dc.contributor.author | Jacobsen, A.S. | |
dc.date.accessioned | 2016-06-01T10:24:09Z | |
dc.date.available | 2016-06-01T10:24:09Z | |
dc.date.issued | 2011-04 | |
dc.identifier.citation | Loh, A.H.P.,Ong, L.Y.,Liew, W.K.,Arkachaisri, T.,Lee, V.K.M.,Narasimhan, K.L.,Jacobsen, A.S. (2011-04). Multiple indomethacin-induced colonic perforations in an adolescent. Singapore Medical Journal 52 (4) : 82-84. ScholarBank@NUS Repository. | |
dc.identifier.issn | 00375675 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/124630 | |
dc.description.abstract | Colonic perforation is an uncommon cause of acute abdomen in paediatric patients, and can present a diagnostic enigma as well as management challenge to the paediatric surgeon. An adolescent developed multiple colonic perforations following a short course of oral indomethacin, requiring emergency hemicolectomy. This is the youngest known case of enteral non-steroidal anti-inflammatory drug (NSAID)-mediated large bowel injury. We review current evidence on NSAID-related enteropathy, and postulate potentiating mechanisms that may have accounted for the unusually rapid clinical course of our patient. | |
dc.source | Scopus | |
dc.subject | Adverse drug reactions | |
dc.subject | Colonic diseases | |
dc.subject | Indomethacin | |
dc.subject | Intestinal perforation | |
dc.subject | Non-steroidal anti-inflammatory drugs | |
dc.type | Review | |
dc.contributor.department | DUKE-NUS GRADUATE MEDICAL SCHOOL S'PORE | |
dc.description.sourcetitle | Singapore Medical Journal | |
dc.description.volume | 52 | |
dc.description.issue | 4 | |
dc.description.page | 82-84 | |
dc.description.coden | SIMJA | |
dc.identifier.isiut | NOT_IN_WOS | |
Appears in Collections: | Staff Publications |
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