Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/122490
Title: DEFINING THE MOLECULAR MECHANISMS IN LUMBAR SPINAL FUSION
Authors: HU TAO
Keywords: spinal fusion chamber, spine, bone morphogenetic protein, gene expression, collagen expression
Issue Date: 28-Jul-2015
Citation: HU TAO (2015-07-28). DEFINING THE MOLECULAR MECHANISMS IN LUMBAR SPINAL FUSION. ScholarBank@NUS Repository.
Abstract: DELIVERY OF LOW DOSE RHBMP-2 BY PEC WAS ABLE TO ACHIEVE SOLID SPINAL FUSION IN LUMBAR SPINAL FUSION MODEL. THIS BONE-INDUCTIVE SYSTEM REDUCED THE ADVERSE EFFECTS SUCH AS SEROMA FORMATION AND ECTOPIC BONE FORMATION, NORMALLY ASSOCIATED WITH SUPRAPHYSIOLOGICAL DOSES OF RHBMP-2 AS SEEN IN CLINICAL PRACTICE. IT HAS THE POTENTIAL FOR USE IN SPINAL FUSION APPLICATIONS AND OTHER BONE TISSUE ENGINEERING PROCEDURES.
URI: http://scholarbank.nus.edu.sg/handle/10635/122490
Appears in Collections:Ph.D Theses (Open)

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