Please use this identifier to cite or link to this item:
https://scholarbank.nus.edu.sg/handle/10635/119784
DC Field | Value | |
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dc.title | Epidemiology of Latency and Relapse in Plasmodium Vivax Malaria | |
dc.contributor.author | ANDREW ARNOLD LOVER | |
dc.date.accessioned | 2015-05-31T18:00:37Z | |
dc.date.available | 2015-05-31T18:00:37Z | |
dc.date.issued | 2014-11-17 | |
dc.identifier.citation | ANDREW ARNOLD LOVER (2014-11-17). Epidemiology of Latency and Relapse in Plasmodium Vivax Malaria. ScholarBank@NUS Repository. | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/119784 | |
dc.description.abstract | Malaria is a major contributor to morbidity and mortality globally. Historically, it has been thought Plasmodium vivax was not a major contributor to disease burden on a global scale. This paradigm is being rigorously re-evaluated, and evidence from diverse settings now suggests that infections with P. vivax can be both severe and fatal. This increasing awareness has highlighted a critical gap: the vast majority of research has been directed towards P. falciparum, and so there has been a decades-long neglect of epidemiological and clinical studies of P. vivax. There exists a large body of historical data on human experimental infections with P. vivax from two major sources: pre antibiotic-era treatment for neurosyphilis (`malariotherapy?), and antimalarial drug trials in prison volunteers. In this thesis, portions of this evidence base have been re-examined and extended using modern epidemiological analyses with two primary main aims: to critically examine this accumulated knowledge base, and to inform current research agendas towards global malaria elimination. | |
dc.language.iso | en | |
dc.subject | Malaria, Plasmodium vivax, Epidemiology, Incubation period, relapse, survival analysis | |
dc.type | Thesis | |
dc.contributor.department | SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH | |
dc.contributor.supervisor | RICHARD JAMES COKER | |
dc.contributor.supervisor | DAVID LOWELL HEYMANN | |
dc.description.degree | Ph.D | |
dc.description.degreeconferred | DOCTOR OF PHILOSOPHY | |
dc.identifier.isiut | NOT_IN_WOS | |
Appears in Collections: | Ph.D Theses (Open) |
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AAL_Thesis_submission_small_sig.pdf | 3.46 MB | Adobe PDF | OPEN | None | View/Download |
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