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Title: | Genomic Analysis Using Short Sequencing Tags | Authors: | CHANG CHENG WEI | Keywords: | chipseq, cofactor, prediction | Issue Date: | 30-Jul-2014 | Citation: | CHANG CHENG WEI (2014-07-30). Genomic Analysis Using Short Sequencing Tags. ScholarBank@NUS Repository. | Abstract: | ChIP-seq is a revolutionary assay used to detect the binding sites of TF in the entire genome, made possible through the rapid advancement in high-throughput sequencing technology. The precision of the binding location of TF can be detected within positional accuracy of +/-200 bp. Motif predictions of TF binding sites tend to yield a much greater accuracy when restricted to regions near ChIP-seq peaks. This thesis studies the problems related to prediction of cofactors by taking advantage of the high resolution of the technology. | URI: | http://scholarbank.nus.edu.sg/handle/10635/119273 |
Appears in Collections: | Ph.D Theses (Open) |
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ChangChengWei_Thesis_HT081728E_signed.pdf | 2.19 MB | Adobe PDF | OPEN | None | View/Download |
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