Please use this identifier to cite or link to this item: https://doi.org/10.1016/0035-9203(91)90384-B
DC FieldValue
dc.titleHorizontal or vertical transmission of hepatitis B virus? A serological survey in family members of hepatitis B carriers in Singapore
dc.contributor.authorTan, C.C.
dc.contributor.authorGuan, R.
dc.contributor.authorYap, I.
dc.contributor.authorTay, H.H.
dc.contributor.authorKang, J.Y.
dc.date.accessioned2014-12-17T08:56:10Z
dc.date.available2014-12-17T08:56:10Z
dc.date.issued1991
dc.identifier.citationTan, C.C., Guan, R., Yap, I., Tay, H.H., Kang, J.Y. (1991). Horizontal or vertical transmission of hepatitis B virus? A serological survey in family members of hepatitis B carriers in Singapore. Transactions of the Royal Society of Tropical Medicine and Hygiene 85 (5) : 656-659. ScholarBank@NUS Repository. https://doi.org/10.1016/0035-9203(91)90384-B
dc.identifier.issn00359203
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/117720
dc.description.abstractHepatitis B serology was performed on 270 family members of 78 hepatitis B carriers and hepatitis B e antigen status determined in those found to be HBsAg positive. The mean age of index patients was 38 years (range 3-74) and that of family members was 28 years (range 1-71). 67 family members (25%) were HBsAg positive. The proportions of family members positive for HBsAg and those negative for HBsAg but positive for anti-HBs and/or anti-HBc were 25% and 20% for children, 10% and 68% for spouses, 36% and 26% for siblings and 29% and 55% for parents. For children of index parents the proportions positive for HBsAg and those negative for HBsAg but positive for anti-HBs and/or anti-HBc were similar whether the index patient was the mother (24% and 24%) or the father (26% and 18%). Our results suggest that horizontal transmission is a significant mode of spread of hepatitis B within the family in Singapore.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/0035-9203(91)90384-B
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentMEDICINE
dc.description.doi10.1016/0035-9203(91)90384-B
dc.description.sourcetitleTransactions of the Royal Society of Tropical Medicine and Hygiene
dc.description.volume85
dc.description.issue5
dc.description.page656-659
dc.description.codenTRSTA
dc.identifier.isiutA1991GM44600031
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