Please use this identifier to cite or link to this item:
Title: Epithelial-mesenchymal transitions: Insights from development
Authors: Lim, J.
Thiery, J.P. 
Keywords: Epithelial-mesenchymal transition
Heart morphogenesis
Neural crest
Issue Date: 1-Oct-2012
Citation: Lim, J., Thiery, J.P. (2012-10-01). Epithelial-mesenchymal transitions: Insights from development. Development (Cambridge) 139 (19) : 3471-3486. ScholarBank@NUS Repository.
Abstract: Epithelial-mesenchymal transition (EMT) is a crucial, evolutionarily conserved process that occurs during development and is essential for shaping embryos. Also implicated in cancer, this morphological transition is executed through multiple mechanisms in different contexts, and studies suggest that the molecular programs governing EMT, albeit still enigmatic, are embedded within developmental programs that regulate specification and differentiation. As we review here, knowledge garnered from studies of EMT during gastrulation, neural crest delamination and heart formation have furthered our understanding of tumor progression and metastasis. © 2012. Published by The Company of Biologists Ltd.
Source Title: Development (Cambridge)
ISSN: 09501991
DOI: 10.1242/dev.071209
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

Google ScholarTM



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.