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Title: Solid-phase functionalization of heterocycles by direct lithiation
Authors: Li, Z.
Ganesan, A. 
Issue Date: Apr-1998
Citation: Li, Z.,Ganesan, A. (1998-04). Solid-phase functionalization of heterocycles by direct lithiation. Synlett (4) : 405-406. ScholarBank@NUS Repository.
Abstract: Lithiation of polymer-bound 3-furanmethanol and 3-thiophenemethanol followed by the addition of electrophiles and resin cleavage afforded 2,4-disubsituted furans and thiophenes respectively in good yield. The 2,4-substituted thiophene can also be further lithiated on solid-phase at C-5 to give 2,3,5-substituted thiophenes.
Source Title: Synlett
ISSN: 09365214
Appears in Collections:Staff Publications

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