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Title: Renal dysfunction in workers exposed to inorganic lead
Authors: Lim, Y.C.
Chia, K.S. 
Ong, H.Y.
Ng, V.
Chew, Y.L.
Keywords: α-1 microglobulin
β-2 microglobulin
Creatinine clearnance
Issue Date: 2001
Citation: Lim, Y.C.,Chia, K.S.,Ong, H.Y.,Ng, V.,Chew, Y.L. (2001). Renal dysfunction in workers exposed to inorganic lead. Annals of the Academy of Medicine Singapore 30 (2) : 112-117. ScholarBank@NUS Repository.
Abstract: Introduction: We studied the relationship between renal dysfunction and occupational lead exposure in a local factory. Materials and Methods: A cross-sectional study with a cohort component was conducted with 55 male workers of a factory producing PVC stabilisers at subjects. Workers from this factory have been followed up with 6-monthly blood lead measurements since 1982. Two indices of overall lead exposure, i.e. the number of times a worker's blood lead exceeded 40 μg/dL (Pb B40) and cumulative blood lead index (PbBint), were obtained from this data. Recent blood lead concentration (PbB) was measured. 4-hour creatinine clearance and various other urinary and serum markers of renal dysfunction were used as effect indices. Results: There was no relationship between PbB and any of the renal markers. However, creatinine clearance decreased significantly (P
Source Title: Annals of the Academy of Medicine Singapore
ISSN: 03044602
Appears in Collections:Staff Publications

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