Please use this identifier to cite or link to this item: https://doi.org/10.1007/BF00397847
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dc.titleUrinary levels of proteins and metabolites in workers exposed to toluene - A cross-sectional study
dc.contributor.authorNg, T.P.
dc.contributor.authorOng, S.G.
dc.contributor.authorLama, W.K.
dc.contributor.authorJones, M.G.
dc.contributor.authorCheung, C.K.
dc.contributor.authorOng, C.N.
dc.date.accessioned2014-12-01T06:57:26Z
dc.date.available2014-12-01T06:57:26Z
dc.date.issued1990-01
dc.identifier.citationNg, T.P., Ong, S.G., Lama, W.K., Jones, M.G., Cheung, C.K., Ong, C.N. (1990-01). Urinary levels of proteins and metabolites in workers exposed to toluene - A cross-sectional study. International Archives of Occupational and Environmental Health 61 (8) : 43-46. ScholarBank@NUS Repository. https://doi.org/10.1007/BF00397847
dc.identifier.issn03400131
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/113699
dc.description.abstractWe measured urinary excretion of albumin and retinol-binding proteins to investigate the occurrence of early renal dysfunction in 45 paint workers exposed principally to toluene, and in the same number of unexposed control subjects matched individually for sex and age. Two biological indicators of personal toluene absorption, namely urine hippuric acid and o-cresol, were also measured in the exposed subjects. A significantly higher level and increased prevalence of elevated retinol-binding protein in the urine of exposed workers was found, whereas no significant difference in urinary albumin concentration was seen between the two groups. Urinary concentrations of retinol-binding protein was correlated (r = 0.399, P < 0.006) with that of o-cresol, but not with hippuric acid or employment duration. The results suggest a dose-dependent early tubular effect due to toluene exposure that might be useful for monitoring individuals exposed to toluene at work. © 1990 Springer-Verlag.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1007/BF00397847
dc.sourceScopus
dc.subjectAlbumin
dc.subjectHippuric acid
dc.subjectO-cresol
dc.subjectRetinol-binding protein
dc.subjectToluene
dc.typeArticle
dc.contributor.departmentCOMMUNITY,OCCUPATIONAL & FAMILY MEDICINE
dc.description.doi10.1007/BF00397847
dc.description.sourcetitleInternational Archives of Occupational and Environmental Health
dc.description.volume61
dc.description.issue8
dc.description.page43-46
dc.description.codenIAOHD
dc.identifier.isiutA1990CF32300007
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