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Title: Homocysteine and retinal vein occlusion: A Population-based study
Authors: Chua, B.
Kifley, A.
Wong, T.Y. 
Mitchell, P.
Issue Date: Jan-2005
Citation: Chua, B., Kifley, A., Wong, T.Y., Mitchell, P. (2005-01). Homocysteine and retinal vein occlusion: A Population-based study. American Journal of Ophthalmology 139 (1) : 181-182. ScholarBank@NUS Repository.
Abstract: To report population data on the association between homocysteinemia and retinal vein occlusion (RVO). Cross-sectional, population-based study. Total serum homocysteine (tHcy) was estimated in subjects attending the second Blue Mountains Eye Study (BMES) (n = 3509, aged >49 years). Its association with RVO (graded from retinal photographs) was examined. Homocysteine was more strongly associated with RVO in younger than older participants. In those aged 15 μmol/l were associated with increased odds of RVO, odds ratio (OR) 3.76; 95% confidence interval (CI) 1.06-13.40, in multivariable-adjusted analyses. Each 1 μmol/l increase in homocysteine was associated with a 7% increased odds of RVO, OR 1.07; CI 0.99-1.17 (P =. 08). This population-based study showed that elevated serum homocysteine is associated with the presence of RVO, independent of other risk factors. © 2005 by Elsevier Inc. All rights reserved.
Source Title: American Journal of Ophthalmology
ISSN: 00029394
DOI: 10.1016/j.ajo.2004.06.084
Appears in Collections:Staff Publications

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