Please use this identifier to cite or link to this item:
|Title:||Factors determining diagnostic yield of endoscopic ultrasound guided fine-needle aspiration for pancreatic cystic lesions: A multicentre Asian study||Authors:||Lim, L.G.
|Issue Date:||Jun-2013||Citation:||Lim, L.G., Lakhtakia, S., Ang, T.L., Vu, C.K.F., Dy, F., Chong, V.H., Khor, C.J.L., Lim, W.C., Doshi, B.K., Varadarajulu, S., Yasuda, K., Wong, J.Y.Y., Chan, Y.H., Nga, M.E., Ho, K.Y. (2013-06). Factors determining diagnostic yield of endoscopic ultrasound guided fine-needle aspiration for pancreatic cystic lesions: A multicentre Asian study. Digestive Diseases and Sciences 58 (6) : 1751-1757. ScholarBank@NUS Repository. https://doi.org/10.1007/s10620-012-2528-2||Abstract:||Background and Aim: The purpose of this study was to determine (1) the diagnostic yield for endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) in patients with pancreatic cystic lesions, (2) additional value of EUS-FNA over EUS alone in the diagnosis of pancreatic cysts, and (3) diagnostic sensitivity and specificity of EUS and EUS-FNA in the subset of patients where histopathology of surgical specimens were available. Methods: All patients who underwent EUS examination for the evaluation of pancreatic cystic lesions in six Asian centres were included in the study. Results: Of 298 patients with pancreatic cysts who underwent EUS, 132 (44.3 %) underwent FNA. In the entire cohort, pseudocysts and intraductal papillary mucinous neoplasm (IPMN) were the predominant cystic lesions. The cytologic yield of EUS-FNA was 47 %. On univariate analysis, factors associated with higher cytologic yield included vascular involvement on EUS, presence of solid cystic component, and increased number of needle passes during EUS-FNA. On multivariate analysis, presence of solid cystic components and increased number of needle passes during EUS-FNA were associated with higher diagnostic yield of EUS-FNA. For pancreatic cysts with a solid component, the diagnostic yield of EUS-FNA increased significantly from 44 % with one pass to 78 % with more than one pass (p = 0.016). In the absence of a solid component, the diagnostic yield was 29 % with one pass and was not significantly different from the diagnostic yield of 50 % with more than one pass, p = 0.081. Conclusion: The cytologic yield of EUS-FNA was 47 %. When a solid component was present in the cyst, doing more than one pass during EUS-FNA increased its diagnostic yield. © 2013 Springer Science+Business Media New York.||Source Title:||Digestive Diseases and Sciences||URI:||http://scholarbank.nus.edu.sg/handle/10635/113479||ISSN:||01632116||DOI:||10.1007/s10620-012-2528-2|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jun 1, 2023
WEB OF SCIENCETM
checked on May 25, 2023
checked on May 25, 2023
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.