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Title: Environmental and biological monitoring of occupational exposure to 1,1,1-trichloroethane
Authors: Tay, P.
Pinnagoda, J.
Sam, C.T.
Ho, S.F.
Tan, K.T.
Ong, C.N. 
Issue Date: Jun-1995
Citation: Tay, P.,Pinnagoda, J.,Sam, C.T.,Ho, S.F.,Tan, K.T.,Ong, C.N. (1995-06). Environmental and biological monitoring of occupational exposure to 1,1,1-trichloroethane. Occupational Medicine 45 (3) : 147-150. ScholarBank@NUS Repository.
Abstract: Fifty workers involved in various degreasing and cleaning processes using 1,1,1-trichloroethane (1,1,1-TCE) were studied with respect to personal and static exposures. In addition, end-of-shift expired air and venous blood samples were taken for analysis of the parent compound. Urinary samples were also obtained at the same time for analysis of its metabolites - trichloroethanol (TCOH) and trichloroacetic acid (TCA). The results show that open/manual degreasing processes generate the highest environmental solvent levels (mean = 819.9 mg/m3; sd = 781.9 mg/m3) followed by jet-spray cleaning (mean = 460.5 mg/m3; sd = 292.4 mg/m3), vapour degreasing (mean = 365.3 mg/m3; sd = 279.9 mg/m3) and ultrasonic degreasing (mean = 134.7 mg/m3; sd = 121.0 mg/m33). Personal exposure levels were well correlated with concentrations of 1,1,1-TCE in end-of-shift expired air (r = 0.81) and venous blood samples (r = 0.88) but only moderately correlated with concentrations of its metabolites in urine (r = 0.49 for TCOH; r = 0.58 for TCA). Static (area) sampleswere poorly correlated with the biological exposure indices studied. © 1995.
Source Title: Occupational Medicine
ISSN: 09627480
Appears in Collections:Staff Publications

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