Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/113416
DC FieldValue
dc.titleCorrecting for baseline differences in the comparison of rates
dc.contributor.authorLee, J.
dc.contributor.authorLee, H.-P.
dc.date.accessioned2014-12-01T06:54:13Z
dc.date.available2014-12-01T06:54:13Z
dc.date.issued1987
dc.identifier.citationLee, J.,Lee, H.-P. (1987). Correcting for baseline differences in the comparison of rates. Computers in Biology and Medicine 17 (5) : 357-362. ScholarBank@NUS Repository.
dc.identifier.issn00104825
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/113416
dc.description.abstractStatistical adjustment of baseline differences (bias attributable to confounding covariates) in the comparison of rates is often carried out by the stratification approach (e.g. the "direct standardization method"). However, this approach is usually not feasible for simultaneous adjustment of more than one confounding covariates given modest sample size. Also, the stratification approach requires grouping a continuous adjustment variable into broad categories, and consequently, residual confounding of the adjusted rates can still occur. These drawbacks can be overcome by multiple regression. This communication considers a statistical procedure for the comparison of occurrence rate of some event across two or more exposure or treatment groups adjusting for one or more confounding covariates. The procedure is based on the multiple logistic regression model. A detailed numeric example to illustrate the application of the method is presented. A computer program to carry out the statistical procedures is available from the authors. © 1987.
dc.sourceScopus
dc.subjectAdjusted rates
dc.subjectClinical trials
dc.subjectComparative studies
dc.subjectConfounding bias
dc.subjectLogistic regression
dc.subjectRate comparisons
dc.typeArticle
dc.contributor.departmentCOMMUNITY,OCCUPATIONAL & FAMILY MEDICINE
dc.description.sourcetitleComputers in Biology and Medicine
dc.description.volume17
dc.description.issue5
dc.description.page357-362
dc.description.codenCBMDA
dc.identifier.isiutNOT_IN_WOS
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