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Title: Changing prevalence of gastroesophageal reflux with changing time: Longitudinal study in an Asian population
Authors: Lim, S.L.
Goh, W.T.
Lee, J.-M.J. 
Ng, T.P.
Ho, K.-Y.
Keywords: Acid regurgitation
Gastroesophageal reflux
Issue Date: Jul-2005
Citation: Lim, S.L., Goh, W.T., Lee, J.-M.J., Ng, T.P., Ho, K.-Y. (2005-07). Changing prevalence of gastroesophageal reflux with changing time: Longitudinal study in an Asian population. Journal of Gastroenterology and Hepatology (Australia) 20 (7) : 995-1001. ScholarBank@NUS Repository.
Abstract: Background: The purpose of the present paper was to study previously obtained population-based data on the prevalence of reflux symptoms in a random sample of community adults in Singapore. This sample was re-investigated 5 years later to determine changes in the prevalence of reflux symptoms. Methods: In 1999, 237 (34%) of the original cohort of 696 persons who were interviewed in 1994, were re-interviewed using a validated Gastrointestinal Symptoms Questionnaire. The original cohort was a race-stratified random sample of residents in a Singaporean town. Reflux was defined as heartburn and/or acid regurgitation occurring at least once a month. Results: Among the 237 respondents (aged 25-89 years; male: female, 49:51; Chinese n = 106, 45%; Malay n = 69, 29%; Indian n = 60, 25%), reflux was reported by 25 respondents, giving a prevalence of 10.5 ± 2.0%. This compared with the prevalence of 5.5 ± 1.5% (odds ratio [OR], 2.2; 95% confidence interval [CI]: 1.0-5.2; P = 0.05) among the same 237 respondents in the 1994 survey. Of the 25 subjects who reported reflux in the current survey, 22 (88.0%) did not complain of reflux symptoms in the 1994 survey. The ethnic-adjusted prevalence of reflux in 1999 was estimated to be 9.9 ± 1.9%. This was an increase above the prevalence in 1994 of 1.6 ± 1.0% (P = 0.051). The upward trend in the prevalence of reflux was not related to age, smoking, alcohol consumption, or increase in bodyweight. Conclusions: There is a rising trend of reflux symptoms frequency in the general population of Singapore over a 5-year period. © 2005 Blackwell Publishing Asia Pty Ltd.
Source Title: Journal of Gastroenterology and Hepatology (Australia)
ISSN: 08159319
DOI: 10.1111/j.1400-1746.2005.03887.x
Appears in Collections:Staff Publications

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