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Title: Solid-phase synthesis of peptidomimetic oligomers with a phosphodiesterase backbone
Authors: Lin, P.
Ganesan, A. 
Issue Date: 3-Mar-1998
Citation: Lin, P., Ganesan, A. (1998-03-03). Solid-phase synthesis of peptidomimetic oligomers with a phosphodiesterase backbone. Bioorganic and Medicinal Chemistry Letters 8 (5) : 511-514. ScholarBank@NUS Repository.
Abstract: An unnatural biopolymer is described in which amino acid side-chains are presented along a negatively charged phosphodiester backbone. For this purpose, a series of phosphoramidite monomers was prepared from chiral 1,2-diols. These were efficiently converted into oligomers using standard coupling conditions on an automated DNA synthesizer.
Source Title: Bioorganic and Medicinal Chemistry Letters
ISSN: 0960894X
DOI: 10.1016/S0960-894X(98)00064-X
Appears in Collections:Staff Publications

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