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https://doi.org/10.1016/S0960-894X(98)00064-X
Title: | Solid-phase synthesis of peptidomimetic oligomers with a phosphodiesterase backbone | Authors: | Lin, P. Ganesan, A. |
Issue Date: | 3-Mar-1998 | Citation: | Lin, P., Ganesan, A. (1998-03-03). Solid-phase synthesis of peptidomimetic oligomers with a phosphodiesterase backbone. Bioorganic and Medicinal Chemistry Letters 8 (5) : 511-514. ScholarBank@NUS Repository. https://doi.org/10.1016/S0960-894X(98)00064-X | Abstract: | An unnatural biopolymer is described in which amino acid side-chains are presented along a negatively charged phosphodiester backbone. For this purpose, a series of phosphoramidite monomers was prepared from chiral 1,2-diols. These were efficiently converted into oligomers using standard coupling conditions on an automated DNA synthesizer. | Source Title: | Bioorganic and Medicinal Chemistry Letters | URI: | http://scholarbank.nus.edu.sg/handle/10635/112076 | ISSN: | 0960894X | DOI: | 10.1016/S0960-894X(98)00064-X |
Appears in Collections: | Staff Publications |
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