Please use this identifier to cite or link to this item:
https://doi.org/10.1074/jbc.M112.403774
| Title: | α-Catenin and vinculin cooperate to promote high E-cadherin-based adhesion strength | Authors: | Thomas, W.A. Boscher, C. Chu, Y.-S. Cuvelier, D. Martinez-Rico, C. Seddiki, R. Heysch, J. Ladoux, B. Thiery, J.P. Mege, R.-M. Dufour, S. |
Issue Date: | 15-Feb-2013 | Citation: | Thomas, W.A., Boscher, C., Chu, Y.-S., Cuvelier, D., Martinez-Rico, C., Seddiki, R., Heysch, J., Ladoux, B., Thiery, J.P., Mege, R.-M., Dufour, S. (2013-02-15). α-Catenin and vinculin cooperate to promote high E-cadherin-based adhesion strength. Journal of Biological Chemistry 288 (7) : 4957-4969. ScholarBank@NUS Repository. https://doi.org/10.1074/jbc.M112.403774 | Abstract: | Background: Cadherin interactions with catenins are crucial for intercellular adhesion. Results: αE-catenin and vinculin cooperate to promote the time-dependent reinforcement of cadherin-mediated adhesions. Conclusion: aE-catenin and vinculin form a mechanoresponsive link between cadherin and the underlying actin cytoskeleton. Significance: The force-dependent modulation of a-catenin and vinculin recruitment contributes to the development of cadherin adhesion strength.© 2013 by The American Society for Biochemistry and Molecular Biology, Inc. | Source Title: | Journal of Biological Chemistry | URI: | http://scholarbank.nus.edu.sg/handle/10635/110800 | ISSN: | 00219258 | DOI: | 10.1074/jbc.M112.403774 |
| Appears in Collections: | Staff Publications |
Show full item record
Files in This Item:
There are no files associated with this item.
SCOPUSTM
Citations
87
checked on Oct 31, 2020
WEB OF SCIENCETM
Citations
85
checked on Oct 23, 2020
Page view(s)
69
checked on Oct 31, 2020
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.