Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.dld.2013.09.025
DC FieldValue
dc.titleImmunohistochemical analysis of metaplastic non-goblet columnar lined oesophagus shows phenotypic similarities to Barrett's oesophagus: A study in an Asian population
dc.contributor.authorSrivastava, S.
dc.contributor.authorLiew, M.S.
dc.contributor.authorMcKeon, F.
dc.contributor.authorXian, W.
dc.contributor.authorYeoh, K.G.
dc.contributor.authorHo, K.Y.
dc.contributor.authorTeh, M.
dc.date.accessioned2014-11-26T09:59:46Z
dc.date.available2014-11-26T09:59:46Z
dc.date.issued2014-02
dc.identifier.citationSrivastava, S., Liew, M.S., McKeon, F., Xian, W., Yeoh, K.G., Ho, K.Y., Teh, M. (2014-02). Immunohistochemical analysis of metaplastic non-goblet columnar lined oesophagus shows phenotypic similarities to Barrett's oesophagus: A study in an Asian population. Digestive and Liver Disease 46 (2) : 170-175. ScholarBank@NUS Repository. https://doi.org/10.1016/j.dld.2013.09.025
dc.identifier.issn15908658
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/110748
dc.description.abstractBackground: Barrett's oesophagus is a premalignant condition, predisposing to oesophageal adenocarcinoma. However, some adenocarcinoma may arise in columnar lined oesophagus without goblet cells. Our aim was to evaluate the biological properties of non-goblet columnar lined oesophagus only and elucidate its relationship with Barrett's oesophagus and associated neoplasia. Methods: Endoscopic biopsies from patients with Barrett's oesophagus (n= 30), non-goblet columnar lined oesophagus (n= 14), Barrett's oesophagus associated high grade dysplasia (n= 6) and adenocarcinoma (n= 4) were selected. Immunostaining for villin, claudin 3 and MUC4 was performed. Statistical analysis was performed and a p value
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.dld.2013.09.025
dc.sourceScopus
dc.subjectBarrett's oesophagus
dc.subjectClaudin 3
dc.subjectColumnar lined oesophagus
dc.subjectMUC4
dc.subjectOesophageal adenocarcinoma
dc.typeArticle
dc.contributor.departmentCANCER SCIENCE INSTITUTE OF SINGAPORE
dc.description.doi10.1016/j.dld.2013.09.025
dc.description.sourcetitleDigestive and Liver Disease
dc.description.volume46
dc.description.issue2
dc.description.page170-175
dc.description.codenDLDIF
dc.identifier.isiut000330570100013
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