1. ScholarBank@NUS
  2. 1. Staff
  3. Staff Publications
Please use this identifier to cite or link to this item: https://doi.org/10.7314/APJCP.2012.13.5.2139
DC FieldValue
dc.titleADPRT Val762Ala and XRCC1 Arg194Trp polymorphisms and risk of gastric cancer in Sichuan of China
dc.contributor.authorWen, Y.-Y.
dc.contributor.authorPan, X.-F.
dc.contributor.authorLoh, M.
dc.contributor.authorTian, Z.
dc.contributor.authorYang, S.-J.
dc.contributor.authorLv, S.-H.
dc.contributor.authorHuang, W.-Z.
dc.contributor.authorHuang, H.
dc.contributor.authorXie, Y.
dc.contributor.authorSoong, R.
dc.contributor.authorYang, C.-X.
dc.date.accessioned2014-11-26T09:59:27Z
dc.date.available2014-11-26T09:59:27Z
dc.date.issued2012
dc.identifier.citationWen, Y.-Y., Pan, X.-F., Loh, M., Tian, Z., Yang, S.-J., Lv, S.-H., Huang, W.-Z., Huang, H., Xie, Y., Soong, R., Yang, C.-X. (2012). ADPRT Val762Ala and XRCC1 Arg194Trp polymorphisms and risk of gastric cancer in Sichuan of China. Asian Pacific Journal of Cancer Prevention 13 (5) : 2139-2144. ScholarBank@NUS Repository. https://doi.org/10.7314/APJCP.2012.13.5.2139
dc.identifier.issn15137368
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/110720
dc.description.abstractObjective: Gastric cancer remains a major health problem in China. We hypothesized that XRCC1 Arg194Trp and ADPRT Val762Ala may be associated with risk. Methods: We designed a multicenter 1:1 matched case-control study of 307 pairs of gastric cancers and controls between October 2010 and August 2011. XRCC1 Arg194Trp and ADPRT Val762Ala were sequenced, and demographic data as well as lifestyle factors were collected using a self-designed questionnaire. Results: Individuals carrying XRCC1 Trp/Trp or Arg/Trp variant genotype had a significantly increased risk of gastric cancer (OR, 1.718; 95% CI, 1.190-2.479), while the OR for ADPRT Val762Ala variant genotype (Ala/Ala or Val/Ala) was 1.175 (95% CI, 0.796-1.737). No gene-gene or gene-environment interactions were found. In addition, family history of cancer and drinkers proportion were higher among cases than among controls (P
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.7314/APJCP.2012.13.5.2139
dc.sourceScopus
dc.subjectADPRT
dc.subjectChina
dc.subjectGastric cancer
dc.subjectPolymorphisms
dc.subjectRisk
dc.subjectXRCC1
dc.typeArticle
dc.contributor.departmentCANCER SCIENCE INSTITUTE OF SINGAPORE
dc.description.doi10.7314/APJCP.2012.13.5.2139
dc.description.sourcetitleAsian Pacific Journal of Cancer Prevention
dc.description.volume13
dc.description.issue5
dc.description.page2139-2144
dc.identifier.isiut000309470100075
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.