Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.mib.2011.10.007
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dc.titlePlasticity in mast cell responses during bacterial infections
dc.contributor.authorChan, C.Y.
dc.contributor.authorSt. John, A.L.
dc.contributor.authorAbraham, S.N.
dc.date.accessioned2014-11-26T09:06:07Z
dc.date.available2014-11-26T09:06:07Z
dc.date.issued2012-02
dc.identifier.citationChan, C.Y., St. John, A.L., Abraham, S.N. (2012-02). Plasticity in mast cell responses during bacterial infections. Current Opinion in Microbiology 15 (1) : 78-84. ScholarBank@NUS Repository. https://doi.org/10.1016/j.mib.2011.10.007
dc.identifier.issn13695274
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/110710
dc.description.abstractMast cells (MCs) have been implicated in orchestrating the host's early innate immune and adaptive immune responses in several models of acute bacterial infections. Most of this activity results in early clearance of the bacteria and timely resolution of infection. However, during chronic infections because of the prolonged nature of MC-bacterial interactions, the role of the MC in determining the fate of infection is markedly more complex. Depending on the nature of the pathogen, severity of infection, and its association with a preexisting inflammatory disease, MCs may promote rather than contain chronic infections and exacerbate their pathological sequellae. © 2011 Elsevier Ltd.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.mib.2011.10.007
dc.sourceScopus
dc.typeReview
dc.contributor.departmentDUKE-NUS GRADUATE MEDICAL SCHOOL S'PORE
dc.description.doi10.1016/j.mib.2011.10.007
dc.description.sourcetitleCurrent Opinion in Microbiology
dc.description.volume15
dc.description.issue1
dc.description.page78-84
dc.description.codenCOMIF
dc.identifier.isiut000301314200013
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