Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.neuroimage.2013.05.119
Title: Time-on-task and sleep deprivation effects are evidenced in overlapping brain areas
Authors: Asplund, C.L.
Chee, M.W.L. 
Keywords: Arterial spin labeling
Attention
BOLD fMRI
Sleep deprivation
Time-on-task
Issue Date: 5-Nov-2013
Citation: Asplund, C.L., Chee, M.W.L. (2013-11-05). Time-on-task and sleep deprivation effects are evidenced in overlapping brain areas. NeuroImage 82 : 326-335. ScholarBank@NUS Repository. https://doi.org/10.1016/j.neuroimage.2013.05.119
Abstract: Both sleep deprivation and extended task engagement (time-on-task) have been shown to degrade performance in tasks evaluating sustained attention. Here we used pulsed arterial spin labeling (pASL) to study participants engaged in a demanding selective attention task. The participants were imaged twice, once after a normal night of sleep and once after approximately 24. h of total sleep deprivation. We compared task-related changes in BOLD signal alongside ASL-based cerebral blood flow (CBF) changes. We also collected resting baseline CBF data prior to and following task performance. Both BOLD fMRI and ASL identified spatially congruent task activation in ventral visual cortex and fronto-parietal regions. Sleep deprivation and time-on-task caused a decline of both measures in ventral visual cortex. BOLD fMRI also revealed such declines in fronto-parietal cortex. Only early visual cortex showed a significant upward shift in resting baseline CBF following sleep deprivation, suggesting that the neural consequences of both SD and ToT are primarily evident in task-evoked signals. We conclude that BOLD fMRI is preferable to pASL in studies evaluating sleep deprivation given its better signal to noise characteristics and the relative paucity of state differences in baseline CBF. © 2013 Elsevier Inc.
Source Title: NeuroImage
URI: http://scholarbank.nus.edu.sg/handle/10635/110325
ISSN: 10538119
DOI: 10.1016/j.neuroimage.2013.05.119
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

27
checked on May 27, 2020

WEB OF SCIENCETM
Citations

27
checked on May 27, 2020

Page view(s)

67
checked on May 30, 2020

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.