Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.neuroimage.2011.08.026
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dc.titleSleep deprivation reduces default mode network connectivity and anti-correlation during rest and task performance
dc.contributor.authorDe Havas, J.A.
dc.contributor.authorParimal, S.
dc.contributor.authorSoon, C.S.
dc.contributor.authorChee, M.W.L.
dc.date.accessioned2014-11-26T08:30:33Z
dc.date.available2014-11-26T08:30:33Z
dc.date.issued2012-01-16
dc.identifier.citationDe Havas, J.A., Parimal, S., Soon, C.S., Chee, M.W.L. (2012-01-16). Sleep deprivation reduces default mode network connectivity and anti-correlation during rest and task performance. NeuroImage 59 (2) : 1745-1751. ScholarBank@NUS Repository. https://doi.org/10.1016/j.neuroimage.2011.08.026
dc.identifier.issn10538119
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/110276
dc.description.abstractSleep deprivation (SD) can alter extrinsic, task-related fMRI signal involved in attention, memory and executive function. However, its effects on intrinsic low-frequency connectivity within the Default Mode Network (DMN) and its related anti-correlated network (ACN) have not been well characterized. We investigated the effect of SD on functional connectivity within the DMN, and on DMN-ACN anti-correlation, both during the resting state and during performance of a visual attention task (VAT). 26 healthy participants underwent fMRI twice: once after a normal night of sleep in rested wakefulness (RW) and once following approximately 24. h of total SD. A seed-based approach was used to examine pairwise correlations of low-frequency fMRI signal across different nodes in each state. SD was associated with significant selective reductions in DMN functional connectivity and DMN-ACN anti-correlation. This was congruent across resting state and VAT analyses, suggesting that SD induces a robust alteration in the intrinsic connectivity within and between these networks. © 2011 Elsevier Inc.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.neuroimage.2011.08.026
dc.sourceScopus
dc.subjectAnti-correlated network
dc.subjectDefault mode network
dc.subjectFMRI
dc.subjectFunctional connectivity
dc.subjectResting state
dc.subjectSleep deprivation
dc.typeArticle
dc.contributor.departmentDUKE-NUS GRADUATE MEDICAL SCHOOL S'PORE
dc.description.doi10.1016/j.neuroimage.2011.08.026
dc.description.sourcetitleNeuroImage
dc.description.volume59
dc.description.issue2
dc.description.page1745-1751
dc.description.codenNEIME
dc.identifier.isiut000298210600097
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