Please use this identifier to cite or link to this item: https://doi.org/10.1002/jso.20954
Title: Outcome after surgical treatment of suspected gastrointestinal stromal tumors involving the duodenum: Is limited resection appropriate?
Authors: Goh, B.K.P.
Chow, P.K.H. 
Kesavan, S.
Yap, W.-M.
Wong, W.-K.
Keywords: Duodenum
Gastrointestinal stromal tumor (GIST)
Mesenchymal tumor
Surgery
Issue Date: 1-Apr-2008
Citation: Goh, B.K.P., Chow, P.K.H., Kesavan, S., Yap, W.-M., Wong, W.-K. (2008-04-01). Outcome after surgical treatment of suspected gastrointestinal stromal tumors involving the duodenum: Is limited resection appropriate?. Journal of Surgical Oncology 97 (5) : 388-391. ScholarBank@NUS Repository. https://doi.org/10.1002/jso.20954
Abstract: Introduction: Present surgical opinion is divided regarding the optimal method for the treatment of duodenal gastrointestinal stromal tumor (GIST) with some supporting the selective use of limited resection (LR) versus others who prefer pancreaticoduodenectomy (PD). Methods: A retrospective review of 22 patients who underwent surgery for suspected GIST involving the duodenum. Results: There were 15 GISTs, 1 leiomyosarcoma and 6 other non-GIST benign submucosal tumors. Seven patients underwent LR and seven underwent PD for GIST. The median follow-up was 42 (range, 2-174) months. Patients who underwent LR versus PD had similar mean disease-specific survival [144 (95% CI, 92-196) vs. 130 (95% CI, 82-127) months, P = 0.808] and recurrence rates (14% vs. 29%, P = 0.515). All recurrences occurred at distant sites. Comparison between LR versus PD demonstrated that LR was associated with a significantly shorter operation time [125 (range, 50-305) vs. 350 (range, 210-465) min., P = 0.001] but similar morbidity rate (23% vs. 43%, P = 0.357). Comparison between GIST and other benign tumors demonstrated that size was the only statistically significant distinguishing factor [8.5 (range, 2.5-18.0) vs. 2.5 (range, 1.5-8.0) cm, P = 0.014]. Conclusion: Benign non-GIST tumors may be distinguished from duodenal GIST as they are smaller in size. LR is a viable treatment option for suspected GIST involving the duodenum. © 2007 Wiley-Liss, Inc.
Source Title: Journal of Surgical Oncology
URI: http://scholarbank.nus.edu.sg/handle/10635/110204
ISSN: 00224790
DOI: 10.1002/jso.20954
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