Please use this identifier to cite or link to this item:
https://doi.org/10.1371/journal.pone.0044206
DC Field | Value | |
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dc.title | MiR-214 Targets β-Catenin Pathway to Suppress Invasion, Stem-Like Traits and Recurrence of Human Hepatocellular Carcinoma | |
dc.contributor.author | Xia, H. | |
dc.contributor.author | Ooi, L.L.P.J. | |
dc.contributor.author | Hui, K.M. | |
dc.date.accessioned | 2014-11-26T08:29:25Z | |
dc.date.available | 2014-11-26T08:29:25Z | |
dc.date.issued | 2012-09-04 | |
dc.identifier.citation | Xia, H., Ooi, L.L.P.J., Hui, K.M. (2012-09-04). MiR-214 Targets β-Catenin Pathway to Suppress Invasion, Stem-Like Traits and Recurrence of Human Hepatocellular Carcinoma. PLoS ONE 7 (9) : -. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0044206 | |
dc.identifier.issn | 19326203 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/110177 | |
dc.description.abstract | The down-regulation of miR-214 has previously been observed in human hepatocellular carcinoma (HCC). Here, we demonstrated the down-regulation of miR-214 is associated with cell invasion, stem-like traits and early recurrence of HCC. Firstly, we validated the suppression of miR-214 in human HCC by real-time quantitative RT-PCR (qRT-PCR) in 20 paired tumor and non-tumor liver tissues of HCC patients and 10 histologically normal liver tissues from colorectal cancer patients with liver metastases. Further qRT-PCR analysis of 50 HCC tissues from an independent cohort of HCC patients of whom 29 with early recurrent disease ( | |
dc.description.uri | http://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1371/journal.pone.0044206 | |
dc.source | Scopus | |
dc.type | Article | |
dc.contributor.department | DUKE-NUS GRADUATE MEDICAL SCHOOL S'PORE | |
dc.description.doi | 10.1371/journal.pone.0044206 | |
dc.description.sourcetitle | PLoS ONE | |
dc.description.volume | 7 | |
dc.description.issue | 9 | |
dc.description.page | - | |
dc.identifier.isiut | 000308577600031 | |
dc.published.state | Published | |
Appears in Collections: | Staff Publications |
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10_1371_journal_pone_0044206.pdf | 2.51 MB | Adobe PDF | OPEN | Published | View/Download |
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