Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.preteyeres.2007.12.001
DC FieldValue
dc.titleDiabetic retinopathy and systemic vascular complications
dc.contributor.authorCheung, N.
dc.contributor.authorWong, T.Y.
dc.date.accessioned2014-11-26T07:50:28Z
dc.date.available2014-11-26T07:50:28Z
dc.date.issued2008-03
dc.identifier.citationCheung, N., Wong, T.Y. (2008-03). Diabetic retinopathy and systemic vascular complications. Progress in Retinal and Eye Research 27 (2) : 161-176. ScholarBank@NUS Repository. https://doi.org/10.1016/j.preteyeres.2007.12.001
dc.identifier.issn13509462
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/109834
dc.description.abstractRetinopathy is the most common complication of diabetes. The assessment of retinopathy signs presents clinicians a unique opportunity to directly visualize and assess the actual morphology of diabetic microvascular damage. Extensive studies have now shown that people with diabetic retinopathy have excess risks of systemic vascular complications, including subclinical and clinical stroke, coronary heart disease, heart failure, and nephropathy. There is also emerging evidence to suggest that diabetic retinopathy may share common genetic linkages with systemic vascular complications. The extant literature, therefore, supports the theory that diabetic retinopathy reflects widespread microcirculatory disease not only in the eye but also vital organs elsewhere in the body. Being a uniquely specific and non-invasively assessable measure of diabetic microvascular damage, retinopathy may also be envisioned as a novel biomarker of vascular disease risk in asymptomatic patients with diabetes. This review summarizes recent studies on the systemic associations of diabetic retinopathy, and discusses their pathophysiological significance and clinical implications. © 2007 Elsevier Ltd. All rights reserved.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.preteyeres.2007.12.001
dc.sourceScopus
dc.subjectCardiovascular disease prediction
dc.subjectComplications
dc.subjectCoronary heart disease
dc.subjectHeart failure
dc.subjectMacrovascular disease
dc.subjectMicrovascular disease
dc.subjectMortality
dc.subjectNephropathy
dc.subjectRetinopathy
dc.subjectStroke
dc.typeReview
dc.contributor.departmentOPHTHALMOLOGY
dc.description.doi10.1016/j.preteyeres.2007.12.001
dc.description.sourcetitleProgress in Retinal and Eye Research
dc.description.volume27
dc.description.issue2
dc.description.page161-176
dc.description.codenPRTRE
dc.identifier.isiut000255104200002
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