Please use this identifier to cite or link to this item:
https://doi.org/10.1016/j.canlet.2012.12.012
DC Field | Value | |
---|---|---|
dc.title | Trefoil factor 1 suppression of E-CADHERIN enhances prostate carcinoma cell invasiveness and metastasis | |
dc.contributor.author | Bougen, N.M. | |
dc.contributor.author | Amiry, N. | |
dc.contributor.author | Yuan, Y. | |
dc.contributor.author | Kong, X.J. | |
dc.contributor.author | Pandey, V. | |
dc.contributor.author | Vidal, L.J.P. | |
dc.contributor.author | Perry, J.K. | |
dc.contributor.author | Zhu, T. | |
dc.contributor.author | Lobie, P.E. | |
dc.date.accessioned | 2014-11-26T07:49:14Z | |
dc.date.available | 2014-11-26T07:49:14Z | |
dc.date.issued | 2013-05-10 | |
dc.identifier.citation | Bougen, N.M., Amiry, N., Yuan, Y., Kong, X.J., Pandey, V., Vidal, L.J.P., Perry, J.K., Zhu, T., Lobie, P.E. (2013-05-10). Trefoil factor 1 suppression of E-CADHERIN enhances prostate carcinoma cell invasiveness and metastasis. Cancer Letters 332 (1) : 19-29. ScholarBank@NUS Repository. https://doi.org/10.1016/j.canlet.2012.12.012 | |
dc.identifier.issn | 03043835 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/109718 | |
dc.description.abstract | Metastasis is the primary mediator of prostate cancer (PCA) lethality and poses a significant clinical obstacle. The identification of factors involved in the metastasis of PCA is imperative. We demonstrate herein that trefoil factor 1 (TFF1) promotes PCA cell migration and invasion in vitro and metastasis in vivo. The capacity of TFF1 to enhance cell migration/invasion is mediated by transcriptional repression of E-CADHERIN. Consideration of targeted inhibition of TFF1 to prevent metastasis of prostate carcinoma is warranted. © 2012 Elsevier Ireland Ltd. | |
dc.description.uri | http://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.canlet.2012.12.012 | |
dc.source | Scopus | |
dc.subject | Epithelial-to-mesenchymal transition | |
dc.subject | Metastasis | |
dc.subject | Prostate cancer | |
dc.subject | Trefoil factor 1 | |
dc.type | Article | |
dc.contributor.department | PHARMACOLOGY | |
dc.description.doi | 10.1016/j.canlet.2012.12.012 | |
dc.description.sourcetitle | Cancer Letters | |
dc.description.volume | 332 | |
dc.description.issue | 1 | |
dc.description.page | 19-29 | |
dc.description.coden | CALED | |
dc.identifier.isiut | 000316775500004 | |
Appears in Collections: | Staff Publications |
Show simple item record
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.